Multimodal Evaluation of Parenchymal and ventricular CSF in Alzheimer’s disease (Oral presentation)
Projects
Glymphatic clearance in AD
Brain clearance in Alzheimer's disease.
Liangdong Zhou, Ph.D., is an Instructor researcher of Biomedical Engineering in Radiology featuring Computational Mathematics, Numerical simulations, Biophysical modeling at Brain Health Imaging Institute (BHII), Department of Radiology in Weill Cornell Medicine.
Dr. Liangdong Zhou earned his doctorate in computational science and engineering for medical imaging from Yonsei University. During his Ph.D. program, Dr. Zhou was trained in mathematical and computational modeling of PDE based inverse problems in medical imaging, including electrical impedance tomography (electrical, EIT), magnetic resonance elastography (mechanical, MRE), and quantitative susceptibility mapping (magnetic, QSM). He then joined Weill Cornell magnetic resonance imaging research institute (MRIRI)—Wanglab—supervised by Dr. Yi Wang's for postdoctoral training in biophysical modeling and magnetic resonance (MR) data acquisition. At Wanglab, Dr. Zhou developed Quantitative Transport Mapping (QTM), a novel perfusion quantification method without using the conventionally required arterial input function (AIF). Then he moved to Dr. Yi Li's lab in Brain Health Imaging Institute (BHII) to gain further training on neuroscience using both MRI and positron emission tomography (PET). He was promoted as an instructor thereafter for research in neurodegenerative diseases with his expertise in multidisciplinary background.
He currently works with Dr. Yi Li and Mony de Leon on the brain clearance of neurodegenerative diseases such as Alzheimer's disease (AD) using multimodal imaging approach. He uses multi-echo T2 relaxometry to map the brain water components for understanding the glymphatic clearance mechanism. He applied his QTM method to quantify the brain clearance function in AD.
Instructor in Biomedical Engineering in Radiology
Brain Health Imaging Institute (BHII) , Department of Radiologt, Weill Cornell Medicine
Postdoc in Neuroimaging, supervised by Dr. Yi Li
Brain Health Imaging Institute (BHII) , Weill Cornell Medicine
Postdoc in Biomedical Engineering, supervised by Dr. Yi Wang
MRI Research Institute (MRIRI) , Weill Cornell Medicine
PhD in Computational Science and Engineering
School of Mathematics and Computing , Yonsei University, Seoul, South Korea
BS in Applied Mathematics
School of Mathematical Scienses, Ocean University of China, Qingdao, China
Control and communication in bodies and brains (CCBB)
Introduction of Alzheimer's disease for medical students with engineering backgrounds , Weill Cornell Medicine, 10-30-2023
Biomedical Engineering Undergraduate Students Winter Immersion
Neurodegeneration Research in BHII , Weill Cornell Medicine, 1-19-2024
Brain clearance in Alzheimer's disease.
Multimodal Evaluation of Parenchymal and ventricular CSF in Alzheimer’s disease (Oral presentation)
Brain CSF clearance measured by phase-contrast MRI and dynamic 18F-MK-6240 PET in Alzheimer's disease (Oral presentation)
CSF fraction measured by MR T2 relaxometry is better than PVS load to associate with amyloidbeta deposition in 11C-PiB PET (Digital poster)
Quantitative Transport Mapping Derived Early and Later Phase Tracer Velocity for Alzheimer's Disease using Dynamic 18F-MK-6240 PET (Poster presentation)
CSF Fraction Mapping Derived from Multi-echo MR FAST-T2 Sequence Could be an Alternative Measure of Total Perivascular Space in the Brain Parenchyma (Poster presentation)